Maybe the knee/illness and lack of practice, but that doesn't even make much sense given the apparent "game plan". There is definitely a change in the play calling this season, seemingly to limit his running. I still don't get why they don't seem to run as much overall though, given the 3 great backs they have. Throwing 37 times today? That is not how this offense works. The OL has looked pretty meh so far, but Harbaugh needs to have a closed door meeting with Roman. He did this same crap years ago with SF. Lamar is not Mahomes. Let Lamar be Lamar.