When it comes to downslope winds in East TN, I would never say never. There are so many possible ways for it to happens. I assume that areas along the mountains of SE TN would have a slightly better chance of that happening, due to the surface winds being SE on the other side of the mountains in that area. I think areas farther to the northeast would be pretty safe from downslope in this situation.
Just to be clear since there is some discussion about this now, this isn't a significant inverted trough. It is very subtle (mainly seen in wind field), but it maybe just enough to help us out a little. Especially in eastern counties. And the northerly flow down the valley could help areas further south with temps, as Jeff mentioned.