DTX and IWX both disagree with the bolded per their AFDs, respectfully.
Disruption of moisture transport is not be the *ONLY* reason, but it has ended up being *A* reason, unfortunately.
The 500mb configuration was never all that favorable for a big dog despite the model runs the day before yesterday, but in the absence of the Tennessee Valley convection, a narrow but quick hitting band of heavy snow would have had a much easier time developing further NW given the instability & forcing that's in place (which is looking increasingly less likely to happen by the hour).