Look up the effects of low testosterone and insulin sensitivity. There's a direct link between obesity, lower testosterone levels and insulin sensitivity.
This plays into the COVID outlook for patients.
https://www.webmd.com/lung/news/20210527/lower-testosterone-in-men-tied-to-severe-covid-cases
And overall, the vast majority – 89% -- of the COVID-19-infected men, including those with mild disease, showed testosterone levels below what’s considered to be the normal range when they were admitted to hospital. The men in the current study with severe COVID-19 had average blood levels of testosterone of just 53 ng/dL when they entered hospital. Any testosterone level of 250 ng/dL or below is considered ‘low’ in adult men.By day 3 of hospitalization, their average testosterone levels dropped even further -- to only 19 ng/dL.