A vigorous shortwave trough is expected to move across the Great Lakes region Wednesday and across New England early Thursday. Ahead of this trough a warm front lifts across the Northeast ushering in higher theta-e air characterized by dewpoints climbing well into the 60's. This will help contribute to an unstable low-level airmass across the region. Very strong jet dynamics will also overspread the region with a 50-60+ knots of wind at 500mb along with a jet streak of 80-90 knots placing the region in the right front quadrant. This will help contribute to bulk shear values in the 40-60 knot range (and even higher off to the West).
A plume of very steep mid-level lapse rates will move across the region during the afternoon, however, it appears this plume will move off the coast and weaken prior to the overnight period (boooooooooooooooo). Regardless mid-level lapse rates may be in the 6-6.5 C/KM during the overnight. Despite being overnight these lapse rates combined high low-level theta-e air should contribute to sufficient instability to aid in thunderstorm develop and aid in the sustaining of thunderstorms across the region.
All in all the potential exists for a fairly robust and widespread severe weather event stretching from New York/Pennsylvania during the daytime and across New England during the late evening and overnight. Damaging winds will be the greatest concern, however, hail would also be a possibility and there could even be the potential for a few QLCS embedded tornadoes.
The biggest question mark right now is there may be a bit of a disconnect between the upper-level trough and sfc cold front.