If you don't have ducts already, probably a lot.
I'd consider minisplits.. I did that at my place (FHW heat so no ducts) and haven't looked back. Cost me about $8K for three rooms of top-brand inverter heatpump minisplits with extra-low-temp option.
I touch down at BDL about 10am tuesday, need to just hit the grocery on the way home and get into the driveway.. after that I don't care.
watching the onset in the PnC has been an interesting view of how much things are wobbling..