Some concerns have come up with regard to vaccine effectiveness on the mutations. Unfortunately, there isn't enough evidence to support either outcome.
Initially it was said that the European strain was more contagious but not more deadly, now we are hearing that may not be the case. Again, not enough evidence to support either as it is hard to know how long this has persisted.
https://www.washingtonpost.com/world/europe/uk-variant-covid-mortality/2021/01/22/86023180-5cd6-11eb-a849-6f9423a75ffd_story.html