Those conditions were the main reason half of Maine was never settled, and is currently labeled "unorganized territory". Opening of the Erie Canal plus "1816-and-froze-to-death" encouraged a lot of NNE hardscrabble farmers to head west during the subsequent decades.
Edit: After 1:15 in the blueberry patch and pruning apple trees, I felt like it had been 2-3 times that long. 2nd Moderda reaction? Don't know but there's lots of spring left so I quit.
Concerning Biden's "optimism", his initial pledge was 100 million vaccinations in his first 100 days. At the current rate of ~3 million/day, we'll be a lot closer to 200 million, with perhaps 80 million fully vaccinated - 30% of adults?