vortmax

More info about RNA virus mutation - another reason mutation isn't always bad: hhmi.org/news/the-flu-viruss-ability-to-mutate-may-sometimes-be-its-downfall The team also combined several genomic technologies to identify mutations that had cropped up as the virus multiplied within the cells. Cells’ responses to infection seemed to be related to the genomic quirks of the infecting virus, the team found. For example, an unmutated virus was more likely to produce lots of viral RNA and less likely to trigger the cellular alarm. Mutated viruses generally had the opposite effect. “That’s where the virus’s high mutation rate becomes a double-edged sword,” Bloom says. “Some of its mutations inevitably foil its hiding mechanisms.” If someone is infected by mutated viruses, the immune system might more easily gain the upper hand than in someone infected by unmutated viruses, he says. “So the initial variation might help determine how an infection proceeds and why the flu affects people so differently,” says Bloom. What’s next is to verify the finding in animals, he says, to see what happens when a full immune system is present.

They said it's likely that won't happen..."Though there’s the very rare chance a virus could mutate to be more aggressive, if anything, RNA viruses are more likely to mutate into a weaker version." https://www.healthline.com/health-news/what-to-know-about-mutation-and-covid-19#Mutations-arent-making-it-deadlier

Researchers have discovered what they described as a "significant" mutation of the novel coronavirus, which they believe "raises the alarm" that the search for a vaccine could become "futile" down the line. The study, published on the biorxiv.org repository, notes researchers were able to analyze a sample of SARS-CoV-2 from India on January 27 and found a mutation that "leads to weaker receptor binding capability." Although this is received as 'bad' news, it's actually good news as this virus may be well on its way to mutate out of infectiousness. This would be the best case scenario.

So what if you're flying into ROC?

I sure hope the world holds China leadership responsible for withholding critical information from the world. Isn't the first time: https://www.ncbi.nlm.nih.gov/books/NBK92479/ And the WHO isn't helping: https://au.news.yahoo.com/coronavirus-truth-behind-world-health-organisation-puzzling-wet-markets-decision-110140700.html Sad.

The hope is that COVID doesn't mutate a lot. If this is the case, a vaccine could last up to 5 years with 'boosters'. Also, I believe we're seeing some significant advances in vaccine development which will further mitigate the seasonality of COVID (and the Flu, and RSV). There's even research for a vaccine to prevent colorectal cancer. Exciting times ahead.

"His supporters are delusional - plain and simple. Absolutely no better than those in Nazi Germany or Mussolini's Italy who supported their regimes but didn't fancy themselves to be "evil". Don't like the name calling?" Normally I ignore absurd posts like this, but I'll bite. No, actually I don't like your name calling and insults. It's immature and quite ridiculous. Calling 50% of the country "no better than those in Nazi Germany or Mussolini's Italy" is just insanity beyond how bad you think our POTUS is. It's so far-fetched and exaggerated that it only emboldens his supporters even more so to vote for him. I could care less what you think of him, besides, I didn't vote for a man, I voted for his policies - and those don't include mass exterminations.

Good, as the States should....

100% that China's #'s are deliberately low. The Chinese government will pay heavily for the havoc they've caused - watch and see how the world turns on them after this is over. I hope their government fails and their people prosper.

I totally agree. The bigger issue is the kids spreading it to their parents & grandparents. If we can get those 5-minute tests widely available by the summer, that would be a huge step in identifying the hot spots.

Why is he a "tool"? He's not too far off. This is CLEARY much more deadly for post-school aged kids. And if you dig into the data for deaths under 25 or even 45, there are significant percentages of an existing condition. Now is it prudent to send kids back to school this current year? I'd say no, let them finish this year home-schooled and restart in Sept. Data as of April 10, 2020 Age group COVID-19 Deaths (U07.1)1 Deaths from All Causes Percent of Expected Deaths2 Pneumonia Deaths (J12.0–J18.9)3 Deaths with Pneumonia and COVID-19 (J12.0–J18.9 and U07.1)3 Influenza Deaths (J09–J11)4 Population5 All ages 4,984 511,424 89 36,423 2,341 4,541 327,167,434 Under 1 year 0 2,727 65 19 0 9 3,848,208 1–4 years 1 552 76 27 1 26 15,962,067 5–14 years 1 809 73 26 0 34 41,075,169 15–24 years 6 4,638 81 87 2 35 42,970,800 25–34 years 46 9,624 86 257 21 106 45,697,774 35–44 years 129 13,847 89 538 44 160 41,277,888 45–54 years 291 26,652 80 1,416 119 375 41,631,699 55–64 years 624 64,579 86 4,247 269 816 42,272,636 65–74 years 1,085 100,368 91 7,397 456 976 30,492,316 75–84 years 1,372 126,612 92 10,139 691 1,025 15,394,374 85 years and over 1,429 161,016 88 12,270 738 979 6,544,503

The good is that the 2nd time isn't as severe. Just like getting the flu vaccine and then contracting the flu virus. The vaccine doesn't prevent you from getting it, it mitigates the symptoms.

This is fairly common with other viruses like RSV. Symptoms are typically much less severe which means the antibodies are there and working. https://www.sciencedaily.com/releases/2016/04/160421145747.htm

RNA/DNA vaccines are the way to go. We need them perfected quickly to get this crap behind us. It's very promising biotech and something that will dramatically impact the seasonal flu as well. I don't think research funding will be an issue anymore. Quick little blurb about one: https://contemporaryclinic.pharmacytimes.com/preventive-care/dna-flu-vaccine-potential-for-universal-protection

That article linked by LakeEffect would support the first scenario - and the most likely, in my non-professional opinion. Hopefully it's not autoimmune, but that would be leading to more sepsis deaths - don't think we're seeing that in the data. Scenario #2 is freaky, but I would imagine autopsies would be showing evidence of this.

This weekend, House Speaker Nancy Pelosi wrote a letter to colleagues saying: "CARES 2 must go further... extending and strengthening unemployment benefits." Several GOP lawmakers, including Sen. Lindsey Graham, R-S.C., had tried to change the language in the $2 trillion-plus stimulus bill last month to remove any incentive for workers to leave their jobs in order to make more on unemployment. The effort failed.

Bro, we know you hate our President. We know he obviously heard about HydroxyC from doctors and we know he mentioned it at a presser. We also know the press & some Govs freaked out about it and we know they have since changed or changing their tunes. It is what it is. Move along and embrace the good news as we learn more about this killer and be thankful the Fed emergency-approved it for use as it appears to be saving lives.

Maybe people from China traveling to Europe in Nov-Dec...infecting Europeans and mutating to the 'European' strain, then Europeans traveling to NYC in Jan-Feb. Sneaky virus.

The epitome of entitlement...agreed - it's human nature to take the path of least resistance and that's why true socialism fails every time.

The Diamond Princess ship was disembarked Feb. 27. It's safe to draw a conclusion now. Just 1 sample of data that's encouraging.

More good news: All 3,711 passengers on the Diamond Princess cruise ship were tested, 712 tested positive, and of those, 331 (46 percent) have never shown outward symptoms, according to Japan’s health agency, which has also been cited by the CDC. Bad news for unknowing transmission, but: Non-symptomatic people can spread the disease, but, “we know that the virus is much more likely to spread from person to person if the infected one is showing symptoms,”

Based on some of the advances in vaccine development using CRISPR tech, I'm thinking we'll see better & quicker responses to pandemics in the future. There are many good things that will inevitably result from this terrible situation. Maybe we'll get ahead of them, even.

Anyone have stats to show how many untested samples there are left? You can't take these numbers at face value unless you know how many real time new cases there are (vs backlog cases).

As long as this thing doesn't mutate a ton the vaccine, when developed, will take care of it for many, many years w/boosters - similar to MMR, Tdap, etc. That's the hope and a good - case scenario.

In light of the current virus situation, it's smart to both support the American people directly via checks and unemployment boosters, as well as providing incentives to both small and large corporations to keep their employees by supplementing a percentage of their income. It takes a large amount of cash ($500B+) to do this - in order to keep things as close to normal as possible when this virus is behind us. Even the Democrats will support this...all the other stuff is just partisan fluff and not necessary at this time. I think there should've been a part 1 and part 2 with the partisan fluff in part 2.